Crystallisation Science and Engineering

What will I learn?
This three-day short course, delivered by academic and industrial experts, will outline the fundamental science and engineering of crystallisation processes.

How will I benefit?
On completion of the course, you’ll have a deeper understanding of crystallisation science and technology to assist in process development and scale-up for the manufacture of crystals with desired properties.

Provisional programme

The course will include case studies and laboratory experimental sessions to demonstrate crystallisation processes, application of advanced process analytical technologies (PATs) and particle characterisation techniques. You’ll also have hands-on opportunities to use crystallisation modelling software.

Day one: Crystallisation Fundamentals

  • Crystallisation route map
  • Nucleation and crystal growth
  • Crystal morphology and habit modification
  • Fundamentals of polymorphism
  • Solid-State Analysis
  • Screening for polymorphs (solid form selection)
  • Characterisation of pseudo polymorphs (TGA, DVS, IGC)
  • Laboratory Demonstrations - D1 - Nucleation kinetics and D2 - Growth kinetics 

Day two: Crystallisation Processes

  • Batch crystallisation: Process development and scale up
  • Hydrodynamics, mixing and heat transfer in crystallisers
  • Continuous crystallisation: Process development and scale up
  • Solvent selection: properties and solubility
  • Post crystallisation unit operations: Filtration and drying

Measurements and Control

  • Particle size and shape measurements and characterisation
  • Control of crystallisation processes for PSD
  • Process spectroscopic techniques (IR, UV-vis, Raman)
  • Laboratory Demonstrations - D3 - Particle characterisation and D4 - Raman spectroscopy

Day three: Measurements & Control cont...

  • Particle properties and performance
  • Fundamentals of co-crystallisation and case studies of recent developments
  • Molecular to crystal science modelling route map
  • Software demonstration: VISUAL HABIT
  • Model-based design of crystallisation process
  • Software demonstration: The gCRYSTAL modules of gPROMS FormulatedProducts

This course is for you if you’re an engineer or scientist working in industries such as agrochemicals, biotechnology, food, fuels, personal care, pharmaceutical and speciality chemicals companies. It is relevant to those involved in crystallisation process development, scale-up, control and operations. It will also be of interest if you’re a postgraduate or post-doc involved in research in the general area of crystallisation.

"Course was good, covered a variety of topics and catered for those in industry and academia" Almac Group Ltd

"It gave me a good understanding of crystal formation and analysis, which was everything I wanted from the course" Infineum UK Ltd

"The course offers a wide variety of topics which should appeal to people involved in all aspects of crystallisation or crystal work" University of Liverpool

Course directors:

Dr Tariq Mahmud - University of Leeds

Dr Xiaojun Lai - University of Leeds

Full Price:


Course fees includes:

  • cost of tuition
  • course materials
  • lunches
  • refreshments
  • course dinner

Faculty of Engineering
University of Leeds
Leeds, LS2 9JT

You are responsible for your own accommodation, if required. A list of hotels close to the University will be sent with your course joining instructions.

+ 44 (0)113 343 8104/2494

CPD, Conference & Events Co-ordinator
CPD Conference and Events Unit
Faculty of Engineering,
University of Leeds,