Crystallisation Science and Engineering

What will I learn?
This three-day short course, delivered by academic and industrial experts, will outline the fundamental science and engineering of crystallisation processes.

How will I benefit?
On completion of the course, you’ll have a deeper understanding of crystallisation science and technology to assist in process development and scale-up for the manufacture of crystals with desired properties.

The course will include case studies and laboratory experimental sessions to demonstrate crystallisation processes, application of advanced process analytical technologies (PATs) and particle characterisation techniques. You’ll also have hands-on opportunities to use crystallisation modelling software.

Day one: Crystallisation Fundamentals

  • Crystallisation route map
  • Nucleation & crystal growth
  • Crystal morphology and habit modification
  • Fundamentals of polymorphism
  • Solid-State Analysis
  • Screening for polymorphs (solid form selection)
  • Characterisation of pseudo polymorphs (TGA, DVS, IGC)
  • Laboratory Demonstrations - D1 - Nucleation kinetics and D2 - Growth kinetics 

Day two: Crystallisation Processes

  • Batch crystallisation: Process development & scale up
  • Hydrodynamics, mixing and heat transer in crystallisers
  • Continuous crystallisation: Process development & scale up
  • Solvent selection: properties and solubility
  • Post crystallisation unit operations: Filtration and drying

Measurements & Control

  • Particle size measurements and characterisation
  • Particle properties and performance
  • Process spectroscopic techniques (IR, UV-vis, Raman)
  • Control of crystallisation processes for PSD
  • Laboratory Demonstrations - D3 - Particle characterisation and D4 - Raman spectroscopy

Day three: Measurements & Control cont...

  • Control of crystallisation processes for PSD
  • Fundamentals of co-crystallisation and case studies of recent developments
  • Molecular to crystal science modelling route map
  • Software demonstration: VISUAL HABIT
  • Population balance modelling of crystallisation processes
  • Model-based design of crystallisation process
  • Software demonstration: The gCRYSTAL modules of gPROMS FormulatedProducts

This course is for you if you’re an engineer or scientist working in industries on crystallisation process development, scale-up, control and operations. It will also be of interest if you’re a postgraduate or post-doc involved in research in the general area of crystallisation.

"Course was good, covered a variety of topics and catered for those in industry and academia" Almac Group Ltd

"It gave me a good understanding of crystal formation and analysis, which was everything I wanted from the course" Infineum UK Ltd

"The course offers a wide variety of topics which should appeal to people involved in all aspects of crystallisation or crystal work" University of Liverpool

Course directors:

Dr Tariq Mahmud - University of Leeds

Dr Xiaojun Lai - University of Leeds

The Energy Institute has approved Leeds University – Faculty of Engineering as an Approved Training Provider.


Full Price:

£1050 on or before 15 December 2017
£1125 after 15 December 2017

Course fees includes:

  • cost of tuition
  • course materials
  • lunches
  • refreshments
  • course dinner

Faculty of Engineering
University of Leeds
Leeds, LS2 9JT

+ 44 (0)113 343 2494
cpd@engineering.leeds.ac.uk

Jenna Kellett
CPD, Conference & Events Co-ordinator
CPD Conference and Events Unit
Faculty of Engineering,
University of Leeds,
Leeds
LS2 9JT